MY PAYING ADS

Saturday, February 7, 2009

Smoke and Allergies: Children

{base article from Lynda Farley...}
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Of special note from below: "Participants with atopic parents were also less likely to have positive SPTs between ages 13 and 32 years if they smoked themselves
(OR=0.18), and this reduction in risk remained significant after
adjusting for confounders. "
I'm not dead certain of the math, but I believe that translates into something like, "Children who were denied exposure to smoking in the home and who avoided smoking themselves as teens suffered a significant increase of over 400% in future and potentially deadly allergic reactions to 11 common inhaled allergens when tested at ages 13 and 32."
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http://tinyurl. com/2mtlkl

By David Holmes21
January 2008J Allergy Clin Immunol 2008; 121: 38-42MedWire News:
Parental smoking during childhood and personal cigarette smoking in
teenage and early adult life lowers the risk for allergic
sensitization in those with a family history of atopy, according to
the results of a study from New Zealand.

Writing in the Journal of Allergy and Clinical Immunology, Robert
Hancox (University of Otago, Dunedin) and colleagues explain
that "the findings are consistent with the hypothesis that the immune-
suppressant effects of cigarette smoke protect against atopy."

Avoiding exposure to cigarette smoke is often recommended to reduce
the risk for allergic sensitization, particularly for children with a
family history of atopic disease, the authors explain. But evidence
for an effect of smoking on allergic sensitization is mixed.

Hancox and colleagues investigated the effect of passive smoking in
childhood and active smoking in adolescence and adulthood on allergic
sensitization in 972 participants in the Dunedin Multidisciplinary
Health and Development Study
, in which a prospective longitudinal
population-based birth cohort was followed-up to age 32 years.

The authors obtained histories of parental atopic disease and
smoking, and monitored personal smoking at multiple assessments
between birth and age 32 years. Atopy was assessed by skin-prick
tests (SPTs) for 11 common inhaled allergens at ages 13 and 32 years.

The team found that the children of atopic parents were less likely
to have positive SPTs at 13 years if either parent smoked (odds ratio
[OR]= 0.55), although the significance of the association was lost
after adjusting for confounders.

Participants with atopic parents were also less likely to have
positive SPTs between ages 13 and 32 years if they smoked themselves
(OR=0.18), and this reduction in risk remained significant after
adjusting for confounders.

The authors write: "We found that children who were exposed to
parental smoking and those who took up cigarette smoking themselves
had a lower incidence of atopy to a range of common inhaled allergens.

"These associations were found only in those with a parental history
of asthma or hay fever."

They conclude: "The harmful effects of cigarette smoke are well
known, and there are many reasons to avoid it.

"Our findings suggest that preventing allergic sensitization is not
one of them."

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